Celestrol

Thunder God Vine – Celestrol May Help in Leptin Resistance

Celestrol is a naturally occurring chemical in plants like the Thunder God Vine. It has been researched extensively as an anti-obesity drug, because of it’s action in helping with leptin resistance. However, the molecular mechanism for this activity is unknown. This plant is one of the hundreds commonly used in Traditional Chinese Medicine. Celestrol is NOT the magic bullet for weight loss but one study done on rats. Leptin is the hormone that stimulates appetite. Celestrol may help reduce appetite safely. However, when Thunder God Vine is used in Traditional Chinese Medicine, TCM, it is always used in a combination of herbs, or formula. This naturally occurring substance known as celestrol is only one of many chemicals in the Thunder God Vine. The supplements now on the market that have concentrated celestrol may not be a safe and effective way to take this chemical. It has no historical use and would never be used alone in one of the oldest herbal medicine traditions.

Newsweek Article

https://www.newsweek.com/traditional-chinese-medicine-thunder-vine-obesity-1104718

Diabetes Journal August 2018

https://www.newsweek.com/traditional-chinese-medicine-thunder-vine-obesity-1104718

 

October is Breast Cancer Awareness Month – New York Times Says Prevention Starts with Diet

Breast Cancer awareness month is here and unless you are living in a bubble, you see pink everywhere.  From foods to football, products show their support with pink ribbons plastered on them.  I saw a pink oatmeal container at the market and now Monday night football.  The entire half time show of the Dolphins-Patriots game honored breast cancer survivors with a huge pink ribbon spread across the football field.  I say “great”, but let’s also concentrate on prevention and not just hope for “a cure”. 


This article, written by a guest blogger, originated in the NY Times Science section, and shows that living a healthy life style can actually decrease your cancer risk.  Chinese Herbs have been used for decades to help with diet, digestion and weight loss.  If you struggle with maintaining a normal body weight, consider adding  digestive enzymes and Chinese herbs to your daily routine for proper digestion and restful sleep.  Sleep rejuvenates your body and provides the vital energy that you may otherwise try to compensate for with extra food. 
(See this article on how restorative sleep can improve weight loss)


by Kath Bartlett MS. L.Ac. –  Ashville, NC
Obesity dramatically increases a woman’s risk of developing breast cancer by 50-100%, the risk increasing “the older the woman gets and the longer she remains obese.” (1) The reason being is that the abdominal fat cells convert steroid (fat soluble) hormones to estrogen. In the breasts, the additional estrogen created binds to the breast cells, promoting “cell division and potentially tumor growth.” (2) Cancer cells are abnormal cell growth: the additional cell division cause the tumor growth. Adipose tissue (fat) contains an enzyme, aromatase, that converts steroid hormones into estrogen. After menopause, the ovaries and pituitary gland are no longer signaling for estrogen production through the monthly menstrual cycle. To compensate, the amount of aromatase in the adipose tissue increases to step up estrogen production. Obese women have higher levels of estrogen production taking place in the body fat of the hips and stomach, which increases during menopause, which raises the risk of tumors developing in the breast.

“Glucose [blood sugar] is the preferred substrate for cancer cells. . . [In a study] mice injected with aggressive mammary [breast] tumors were placed on 3 diets. After 70 days 95% of the mice on the low-sugar diet were alive. Of the mice on the moderate-sugar diet 67% were alive. And only 33% on a high-sugar diet were alive. Also ‘moderate’ alcohol consumption is associated with elevation in the risk for breast cancer from 50-100%.” (3)

Phytoestrogens have a chemical structure similar to estrogen. They bind to the receptor sites on the breasts, preventing the body’s estrogen from binding and causing tumor cell growth. The phytoestrogens that bind to the breast cell estrogen receptor sites have a weaker influence on breast cell production, so that it is less likely that tumors will form. Common food sources of phytoestrogens include: soy (tofu, tempeh, miso), flax and raw pumpkin seeds, clover and mung bean sprouts. Avoid powdered soy concentrate, these have caused some to develop Hashimoto’s thyroid disease. (4)

Studies have shown that phytoestrogens increase the effectiveness of breast cancer treatments. Borage oil has shown to decrease the growth of breast cancer cells. (5)

Eating an organic diet, and limiting exposure to chemicals, including household cleaners, detergents, pesticides, food packaging (plastics leach into foods, especially when warm foods are put into plastic containers) is also important to reduce cancer risk. Chemicals and pesticides can change the DNA of cells, causing them to mutate into cancer cells. Studies have shown higher levels of pesticides and pollutants in fat and blood of women with breast cancer than in healthy women.

1-6. Lahans, T. Integrating Conventional and Chinese Medicine in Cancer Care. Elsevier 2007; 92-102.

Sleep More For Natural Weight Loss

Natural Sleep aids help with Weight LossScientists have known for years that sleeping more can actually help you lose weight.  There are many studies to support this conclusion.  One such study published in  2005 which included 8000 adults over several years found that less sleep corresponded to greater risks of weight gain.  Is the answer to the American obesity problem in the bedroom?  It's true that eating and sleeping cannot really occur at the same time.

The American Journal of Clinical Nutrition studied a small group of men and women and measured their food intake over 48 hours periods.  One period of time included 8 hours of sleep and another in which the participants slept only 4 hours.   After the night of less sleep the men consumed more than 500 extra calories or approximately 22% more.   

The University of Chicago did a similar study last year and and similar findings in both men and women.  The less sleep the more calories eaten, particularly carbohydrates.   Makes sense to me, when I haven't gotten a good nights sleep I tend to make up for my lack of energy with food.   Some studies blame the gain on hormones.  They argue decreased sleep creates a spike in ghrelin, a hormone that stimulates appetite and an increase in leptin, which signals satiety.  But there seems to be no consensus yet.  Regardless, sleep aids such as Chinese herbs can help you stay asleep and give you the rest you need,  without side-effects or additional calories.  Prescription sleep aids in comparison with placebo pills only provided 11.4 minutes of additional rest but then, that is a subject for another bog. 

What do you think?  Does a night of better sleep equal less food intake the next day?

 

http://www.ncbi.nlm.nih.gov/pubmed/18719052  Eur J Endocrinol. 2008 Dec;159 Suppl 1:S59-66. Epub 2008 Aug 21. Sleep and the epidemic of obesity in children and adults.

Licorice for Weight-Loss? I Am Skeptical

Chinese herb for weight loss, pms and insomnia

Who really needs another article about weight loss plans and products? We’re inundated with advertising on weight loss supplements and the last thing we need is more of the same.  Alas,  I’m asked all the time, “Don’t you have herbs for weight loss?”  People who know me, know I would never suggest Chinese herbs for quick fix weight loss. I’m resigned to the good old fashion diet, eat more veggies, cut the carb’s and do some exercise. There is simply no magic bullet. Chinese herbs are great for a kick start and can help with “draining damp” and “moving qi” or in layman's language "a little clean-out" but even then lifestyle changes are still necessary.    


Then this study comes along and suggests that the oil in a common herb/food we know as licorice, can reduce total body fat and visceral fat.  Wait, I'm a skeptic.  What do you mean? All this time licorice has been masking as Chinese medicine when really it’s a weight loss herb?…. 

 

Licorice contains hydrophobic flavonoids and researchers have been studying these flavonoids for years. Many herbs contain flavonoids and they are a major ingredient in Chinese medicine.   A recent clinical trial with 56 men and 28 postmenopausal women participating used licorice in concentrated extract capsules.  Having changed no other aspect of their lives, all lost weight.

In this trial, some participants were given a placebo capsule and others took capsules of 300 mg of the licorice extract, once daily for eight weeks. The researchers  found that the non- placebo group had decreases from baseline body weight and body mass index after the 4 and 8 weeks mark of treatment.  Other studies on the Chinese herb licorice have seen similar results with LDL cholesterol reduction.

The  researchers of  this study concluded, “that the observed reduction in body weight and fat could be caused by increasing energy expenditure through the enhancement of beta-oxidation and inhibition of lipogenesis.” Further studies are always necessary.  But the researchers also remarked “ that supplementation (with licorice) may prevent or ameliorate obesity and metabolic syndrome when combined with lifestyle modifications including diet and exercise."

Although this may not be a definitive way to lose weight Chinese herbs prove again to be superb health supplements. Whether you are trying to reduce cholesterol or lose weight, Chinese herbs have benefits you may never have thought about.  

I always provide links to the original studies so take a detour here if you want to see the whole study.