Curcumae, A Chinese Herb Proves To Be Cardio-Protective

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From the American Journal of Cardiology, April 2012

 

More great research results on the Chinese herb curcumae!

 

This herbal remedy was yet again put to the test, this time in a study on patients who had coronary artery bypass grafting.

Chinese herbs for osteoarthritis

 

Also known as Yu Jin or Tuber Curcumae, (curcuma), this remarkable herbal supplement has been used in Chinese medicine for centuries. Curcumae, found in tumeric, has been extensively studied for its blood moving abilities. 

 

It is well established that myocardial infarction, (heart attacks) are associated with a coronary artery bypass grafting procedure.  As a result of the poor outcomes of patients who have this grafting procedure, a study on the Chinese herb curcumae was undertaken to  evaluate whether this Chinese herbal remedy for blood stasis could be considered a cardio-protective therapy. 

 

"Previous studies have shown that curcuminoids decrease proinflammatory cytokines during cardiopulmonary bypass surgery and decrease the occurrence of cardiomyocytic apoptosis after cardiac ischemia/reperfusion injury in animal models."

 

The aim of this study done was to evaluate whether curcuminoids, one of the chemical constiuients in curcumae could prevent heart attackes compared to a placebo. 

 

The conclusion:  4 grams of curcumin per day demonstrated a significant decrease in heart attacks after bypass grafting, compared with a placebo.   Postoperative C-reactive protein, levels were also lower in the curcuminoid than in the placebo group.

 

The antioxidant and anti-inflammatory effects of curcuminoids may account for their cardioprotective effects shown in this study

 

Reference:   Study Evaluated Effects of Curcuminoids on Acute Myocardial Infarction

Wongcharoen W, Jai-aue S, Phrommintikul A, et al. Effects of curcuminoids on frequency of acute myocardial infarction after coronary artery bypass grafting. Am J Cardiol. April 3, 2012;[epub ahead of print]. doi: 10.1016/j.amjcard.2012.02.043.

Transparency In Supplement and Food Should Be a Priority

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At Pacific Herbs we believe WHOLE HEATEDLY in transparency.  We believe you should know what is in our Chinese herb products and what is not!    We tell it all because we know we have the highest quality control standards, ISO/GMP approved, natural herbal products on the market. We tell you where and how are herbs are manufactured.  We provide test result information and we use only purified water to process our herbs, no solvents! Who would want an herbal supplement that is not transparent in their standards?

This is information every consumer has a right to know!  The same goes for our food supply.   Wait, it is the same thing, herbs are food too.

Anyway, the citizens of California have an unprecedented opportunity to improve our nation’s food system.  This week, the California Secretary of State placed the California Right to Know Initiative for GMO Labeling on the November ballot. 

The saying “As California Goes, So Goes the Nation” could be happening this November.  When voters pass this GMO labeling of food ingredients we will have true transparency in our food supply. Consumers should push for the same standards in their herbal products.  We are proud to be a leader in this evolution in the natural products industry. 

I look forward to updating you in November.

Magnesium Stearate, The Dirty Little Secret of Supplements

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We believe quality products should NOT have fillers. 

The dirty little secret of the supplement industry is:

a filler is known as Magnesium Stearate.  Nearly every supplement contains it.

I often get questions about the most commonly found additives and filler, magnesium stearate.

Here are a few answers to the most common questions.

What is Magnesium Stearate?    An inactive filler, also known as magnesium salt,  used in most of the natural health supplements and herbal remedies on the market today. 

Where does Magnesium Stearate come from?  Magnesium Stearate is a bi-product of fatty acids, both animal and vegetable sources.  Stearic acid and calcium stearate are made by hydrogenating cottonseed or palm oil.  These fatty substances coat every particle of the nutrients, so the particles will flow rapidly.

 

Cottonseed oil has the highest content of pesticide residues of all commercial oils; cotton crops are heavily sprayed. In the hydrogenation process, the oil is subjected to high heat and pressure in the presence of a metal catalyst for several hours, creating a hydrogenated saturated fat. Hydrogenated vegetable fats contain altered molecules derived from fatty acids that may be toxic.

 

The metal catalyst used in the hydrogenation process may also contaminate the stearates produced (see Erasmus, Fats, and Oils). While toxicity is one problem, decreased absorption is another.

 

In a study published in the Journal of Pharmaceutical Technology, the percent dissolution for capsules after 20 minutes in solution went from 90% without stearates to 25% with stearates. This delays the absorption of nutrients. Individuals with impaired digestion may have particular difficulty absorbing nutrients coated with stearates.

Another problem with stearates: concentrated doses of stearic acid suppress the action of T-cells, a key component of the immune system. The article “Molecular basis for the immunosuppressive action of stearic acid on T cells” appeared in the journal Immunology in 1990. Thus, prolonged administering of magnesium stearate at a high dosage weakens the immune system over a period of time.

 

Why do companies use it?  Magnesium Stearate is used as a lubricant so ingredients in supplements and vitamins don’t stick to the machinery during compression and mixing. When machines are working optimally, without clogging, production schedules and profitability can be controlled.   

 

Who regulates Magnesium Stearate?   The subcommittee of Codex Alimentarius, the world authority on international food standards has regulated magnesium stearate as a food additive. NO  Exposure limits have been established for Magnesium Stearate by OSHA or ACGIH.

Are regulations changing?   Yes, various committees on food additives are now looking for toxicity data on magnesium stearate.  Data has yet to be collected.

At the time of this writing, there is no clinical study data on how much magnesium stearate is too much and what constitutes a toxic load for human consumption.

Your healthiest choice is a herbal supplement and vitamin supplement without magnesium stearate.  Pacific Herbs uses no fillers or stearates in any of our products.   We package everything in airtight, moisture tight packets to preserve our natural herbal extracts and avoid the use of fillers, binders, and other unnecessary chemical ingredients.

Ginseng Fights Fatigue Says Mayo Clinic

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natural herbal energy boostersNeed more energy, REAL energy that sustains you and not just a quick jolt of caffeine?   The most famous Chinese herb, ginseng, now has more proof on its fatigue fighting abilities.  

According to the Mayo Clinic, American Ginseng taken for 8 weeks can help decrease cancer-related fatigue symptoms.

This latest study was done in 40 community medical centers in the U.S and Canada on 364 cancer patients.  Half of the patients studied were undergoing cancer treatment at the time of the study and the other half had already completed cancer treatment.

Ginseng has been used in traditional Chinese medicine as a natural energy booster, libido booster and overall tonic herb for thousands of years. These new findings, just presented at the American Socity of Clinical Oncology annual meeting found the study participants’ experienced

 "Significant Improvement" in their general exhaustion levels with no apparent side effects.  

Mayo researcher Debra Barton stated "After eight weeks, we saw a 20-point improvement in fatigue in cancer patients, measured on a 100-point, standardized fatigue scale." "Cancer is a prolonged chronic stress experience and the effects can last 10 years beyond diagnosis and treatment," she said. "If we can help the body be better modulated throughout treatment with the use of ginseng, we may be able to prevent severe long-term fatigue."

Along with ginseng's energy boosting benefits it also has been researched and concluded to decrease inflammation and regulate levels of coritisol (a common stress hormone). Energy Booster Herb Pack by Pacific Herbs is a perfect addition for anyone dealing with fatigue because it contains a high dose of ginseng. This energy drink is safe, delicious easy to take and perfectly packaged for everyone on the run.  Energy Booster Herb Pack has No caffeine, NO sugar and NO fillers. Energy booster can be taken as a energy drink or just straight in the mouth. 

Harvard Unlocks Secrets of Chinese Herbs

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Harvard School of Dental Medicine has discovered the secret behind an herb used in Chinese herbal medicine.  The herb commonly known as Chang Shan, is a type of hydrangea with a bioactive ingredient that can treat autoimmune disorders.  This is not the first time a Chinese herb has been found to have chemical constituents with significant health benefits.  Most drugs today have their origins in phyto or plant chemicals.  

Chinese medicine has been using plants, insects, fish and shell fish for more than 2,000 years to treat mankind’s illnesses.  Learning the secrets behind the power of these herbs is still an emerging field and scientists are continually learning how various herbal compounds in plants block or stimulate pathways in the body, triggering other reactions.  

In this case, the hydrangea plant contains halofuginone (HF) a compound which blocks the development of a harmful class of immune cells called TH17 cells. These cells have many implications in autoimmune disorders.

“HF prevents the autoimmune response without dampening immunity altogether,” said Malcolm Whitman, a professor of developmental biology at Harvard School of Dental Medicine and senior author on the new study. “This compound could inspire novel therapeutic approaches to a variety of autoimmune disorders.”

Traditional Chinese Medicine is proving more amazing everyday.

This study involved an interdisciplinary team of researchers at Harvard-affiliated and Massachuetts General Hospital and published in Nature Chemical Biology, Febuary 2012.

Prior research had shown that HF reduced scarring in tissue, scleroderma (a tightening of the skin), multiple sclerosis, scar formation, and even cancer progression. “We thought HF must work on a signaling pathway that had many downstream effects,” said Keller.

Recognized only since 2006, Th17 cells are “bad actors,” implicated in many autoimmune diseases such as inflammatory bowel disease (IBS), rheumatoid arthritis (RA), multiple sclerosis (MS), and psoriasis. The researchers found that minute doses of HF reduced multiple sclerosis in a mouse model. As such, it was one of a new arsenal of drugs that selectively inhibits autoimmune pathology without suppressing the immune system globally.

Click here to browse our line of natural and traditional Chinese Herbs.

This research was funded by the National Institutes of Health and Harvard University.

Reference:  http://news.harvard.edu/gazette/story/2012/02/secrets-of-ancient-chinese-remedy-revealed/

 

Fascinating Facts On Chinese Herbs

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Chinese herbs for sleep and menopauseWhat do I find most fascinating about Chinese medicine and Chinese herbs?  Maybe its because Chinese herbs are the oldest medicine on earth.  Practiced for nearly 5000 years. 

One of the oldest Chinese herbal text is the Shen Nong Ben Cao translated it is, “The Divine Farmers Materia Medica”.   This foundation book in Traditional Chinese Medicine (TCM) is the book from which all others are derived.  

I love history.  The ability to read a 2000 year old book on the pharmacologocial activities of more than 365 plant, mineral, fish, shell fish, animal and insects is simply, AMAZING to me.   (This ancient herbal medicine text was written circa 30 AD.)  The use of plants and other pharmacologocial agents found in nature was explained with three key statements from the Shen Nong Ben Cao:

 

The highest level physician helps the patient fulfill their destiny.   “The upper class of medicines…..govern the nourishment of destiny and correspond to heaven…., If one wishes to prolong the years of life without aging, one should” use these. Sheng Nong Ben Cao 

Upper Class or superior drugs:

Superior drugs at the time of the Sheng Nong Ben Cao were those found to be nontoxic, and could be safely taken in large amounts for extended periods.  Today we know them as tonics. (Approximately 120)  Well-known superior drugs include:  ginseng, licorice, di huang (root of Rehmannia), huangqi (root of Astragalus), wu wei zi (fruit of Schisandra), gan cao, (licorice) sesame seed, magnolia flower, ling zhi (Ganoderma), fu ling or poria, Chinese date (fruit of Ziziphus jujuba.), Job’s tears [seed of Coix.) and duzhong (bark of Eucommia).  All of these superior herbs can be found in one or more of Pacific Herbs products.

“The mid-level physician treats constitution and helps the patient nourish their original nature.” Sheng Nong Ben Cao    

“The middle class of medicines govern the nourishment of one’s nature and correspond to man. …If one wishes to prevent illness and to supplement depletions and emaciations, one should” use these.

Middle Class Drugs:  (120 drugs) Middle class drugs are those that could be toxic or nontoxic, depending on usage. This included:  ginger, mahuang or ephedra herb (Ephedra), danggui (Angelica sinensis), jixuecao or gotu kola, kuandonghua or coltsfoot flower (flower of Tussilaqo), yinyanghuo (herb of Epimedium spp.), haizao (Sargassum), hehuan (bark of Albizzia julibriss), gaoben, and zhuling or polyporus [sclerotium of Polyporus umbellatus.

The lowest level physician treats symptoms only.

“The lower (class of) medicines….govern the treatment of illness and correspond to earth. If one wishes to remove cold, heat and (other) evil influences (from the body), to break accumulations, and to cure illnesses, one should base (one’s efforts) on (drugs listed in) the lower (class of this) manual.” Sheng Nong Ben Cao 

Inferior drugs are toxic, and are used for treating diseases and should not be used for extended periods  .Inferior drugs (approx 125  include fu zi and wu tou, which are roots of aconite (Aconitum carmichaeli), rhubarb root (root and rhizome), bai tou weng (root of Pulsatilla chinensis), lian qiao or forsythia fruit (Forsythia), qing hao, croton seed (fruit of Croton), guan zhong (rhizome of Dryopteris), and lang dang zi (Hyoscyamus niger).

 

Many of the drugs in the Shen Nong Ben Cao are still being used today for the same medicinal reasons as the time the information was first written down.  Two thousand years, their rationale can be scientifically justified.  For example, the use of haizao (Sargassum) for the treatment of swelling of the neck (goiter) can be explained by its high content of iodine.  There are endless examples. More than enough for another blog.

Some things never change.  Even after a few thousand years.

Alcohol Abuse Reduced With This Chinese Herb

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herbs for alcohol

Are you struggling with alcohol abuse? Would you believe an herb (that grows as fast as weeds) could help you cut down your drinking habit?  Could this herbal alternative for alcoholics become a reality?

A Chinese herb that has been available for hundreds of years now has a new published study from  McLean Hospital and Harvard Medical School found this Chinese herb helps alcohol drinkers reduce their intake. The study was recently published in Drug and Alcohol Dependence.

"It didn't stop the drinking," says researcher David M. Penetar, PhD, assistant professor of psychology, "they still drank, but they drank less."

Kudzu (Pueraria lobata)  has been used in Traditional Chinese Medicine and has references dating back to 600 A.D.   For the past 1400 years it has an excellent safety record.

Many tout the extract from kudzu, known as puerarin, as  a hangover remedy. Best of all, this all natural herbal alternative has no side-effects and if very inexpensive.  A weeks supply can cost as little as $6.00

When those in the study treated with puerarin they drank about a beer less than when they were treated with placebo.  On average, the men and women drank 3.5 beers after placebo and 2.4 after puerarin.

The National Institute on Alcohol Abuse and Alcoholism funded the study. Even though this study was a small sample size, the study was designed well and the research outcomes validate what many have known for generations.   Chinese herbs can provide "Wellness For Centuries."

Wall Street Journal Reports on Placenta Popularity

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After nine months of gestation and then birthing a child, a women has every right to be exhausted.  What every new mother needs is a diet rich in nutrients and blood building foods to replenish her body.  The placenta is the secret that can return a woman’s vitality quickly.  

I’m happy to see the Wall Street Journal report on what seems incredulous, eating your placenta.   American hospitals have treated childbirth as practically a disease that needs medical intervention for decades. This growing phenomenon, of eating the placenta is as natural as childbirth and a welcome return to the wisdom of women.

A placenta holds a wealth of nutrients and should never be disregarded as medical waste.

Here’s the blogs I wrote on Eating Your Placenta, more than a year ago.   Enjoy!

Never quite sure what will inspire me to write a blog but seeing this video today did the trick.  This blog is about the human placenta and why women are now calling  “a placenta cooking lady” to prepare their placenta’s into pills to ingest after childbirth.   The placenta is attached to the fetus via the umbilical cord.  Once the baby is born the placenta and cord are considered medical waste (so we’re told) at the hospital.  We’ve known for some time the  umbilical cord  is a source of stem cell research and many wealthy parents now have the cord frozen and stored, a insurance policy of sorts for future medical needs.  Recently, in a return to ancient wisdom and in conjunction with science we are relearning about the tremendous nutritional value of the human placenta.  Chinese Medicine has understood this value for generations. Ingesting dried placenta in pill form can help a new mother recuperate from childbirth and reclaim some lost blood and nutrients.

 

You can have your placenta cooked, dried and placed into pills to supplement your child birth recovery.  Those that have used  placenta pills after birth swear they have a shorter recovery from postpartum hemorrhaging, more energy from replenished nutrients, increased milk production and no post-partum depression. In fact, a good friend of mine recently gave birth and she has just finished taking her placenta pills.  This was the first time she had placenta prepared into pills and she reported feeling energized and healthier than after her previous child births.  She said it was a little like a caffeine type energy boost without the caffeine and she had an extremely easy recovery overall.  This was her sixth child!

 

According to Traditional Chinese Medicine, placenta is considered a powerful and sacred yang tonic. The placenta is cooked with a few herbs and wine.  Wine in Chinese medicine has a dispersing action and therefore helps to distribute the placentas nutrients throughout the women’s body.  The placenta is full of natural oxytocins which are responsible for contracting the uterus, it also contains  hormones which is believed to be the reason it helps with postpartum depression.  Historically Chinese Medicine has used human placenta for those who have low energy.  Interestingly, it is the only meat that comes from life, not death and other mammals do eat their placentas.  Maybe the animal kingdom has something to teach us.

Check out this link at Time Magazine, there is a short video showing the placenta being prepared,  in case you’ve never seen one.

Women Want Non-Medical Treatment For Menopause Symptoms

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Studies now state the obvious!  Menopausal women prefer non-medical treatment for their menopause symptom relief and want more support from their doctors.  This was the finding in a February Journal of International Obstetrics and Gynecology.

This community based study looked at 4407 women aged 45 to 54 living in north east Scotland. The participants were asked to complete a questionnaire about their menopausal symptoms and their management.

The questionnaire included a symptom checklist which asked about problems such as stiff joints, aches and pains, headaches, vaginal dryness, hot flushes, night sweats, depression, anxiety, mood swings, decreased sexual interest and menstrual symptoms.

Participants were asked whether they had experienced the symptom in the last month and how bothered they were by this.

The study found that nearly half of the women (46.7%) experienced hot flushes, 46.4% night sweats and 28.2% vaginal dryness. Approximately two-fifths of women reported these symptoms as quite a bit or extremely bothersome.

Surgically menopausal women (participants who have had a hysterectomy and/or oopherectomy) reported the most bother from menopausal symptoms and the greatest frequency of bothersome symptoms.

The study also looked at the different management strategies women adopt, from HRT to alternative therapies and social support. It found that the most common management strategy used by menopausal women was social support through talking to friends or family. This was reported by more than 60% of women.

Moreover, the questionnaire found that women reported taking vitamins, minerals and supplements and herbal remedies rather than HRT, for example, 38% of postmenopausal women had used herbal remedies.

Dr Lisa Iversen, Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen and co-author of the paper said:   “Our results provide a powerful reminder that the menopause is a time of life when women experience numerous symptoms, many of which are bothersome.”

“We found that many women used non-medical approaches to help relieve the symptoms suggesting a large need for effective non-hormonal management options for menopausal women.”

John Thorp, BJOG Deputy-Editor-in-Chief added:

“The results of this questionnaire show that women during the menopause face many different symptoms and have different coping strategies,

“As so many women use herbal remedies,(approx. 38%)  it is important that they are tested for efficacy and safety to the same standard as hormone replacement therapy.”

Couldn’t agree with that last statement more.  Check out Menopause Relief Herb Pack, for natural Menopause Relief the most trusted and tested herbs used safely for centuries.    (See how they are tested here.)

 

 

This Chinese Herb and Common Spice Lowers Blood Sugar for Type 2 Diabetes

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Chinese herbs for diabetesThe rise in diabetes in the Western world is out of control.   Too many folks seem to ignore the role of diet in prevention and treatment of diabetes and yet something as simply as cinnamon consumption may be an way to improve blood glucose levels.

Cinnamon is a common spice and Chinese herb used in Traditional Chinese Medicine (TCM) for centuries.  Cinnamon bark and twigs are often used in Chinese herbal medicine to enhance digestive function, promote the movement of qi, disperse the cold and fortify the kidney energy and pancreas.

A recent study from Germany published in the European Journal of Clincal Investigation shows a water soluble cinnamon extract can reduce fasting blood sugar levels in patients with type 2 diabetes.

The cinnamon  (known as the Chinese herbs Gui Zhi and Rou Gui)  results further add to a growing body of clinical evidence demonstrating supplementation with cinnamon bark and twig extract may play an important role in managing blood sugar levels and improving insulin function.

The  study  done at the University of Hannover was both placebo controlled  and double-blind, designed to determine the effect of a water-soluble cinnamon extract on glycemic control and cardiovascular risk factors in patients with type 2 diabetes. A total of 79 patients with type 2 diabetes not on insulin therapy but treated with oral medication or diet therapy were randomly assigned to take either a cinnamon extract or placebo capsule three times daily for four months. The cinnamon capsule contained 112 mg of water-soluble extract, an equivalent of one gram of cinnamon powder. The cinnamon extract group experienced a significant reduction in fasting plasma glucose levels (10.3%) versus the placebo group (3.4%). Changes in HbA1c and lipid profiles were not statistically significant.

“This study, together with a recent clinical trial utilizing Cinnulin PF, provides compelling evidence for the beneficial effects of a water-soluble cinnamon extract on blood sugar levels,” stated Tim Romero, executive vice president, Integrity Nutraceuticals International, marketer of Cinnulin PF. “We are excited to see in the coming months results of studies underway that further substantiate the efficacy and safety of Cinnulin PF.”

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Reference: American Botanical Council     http://cms.herbalgram.org/herbclip/257/review43853.html

 

More studies on Curcumin: 

Phase II trial of curcumin in patients with advanced pancreatic cancer

GoJi Berries For More Energy And Less Weight

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Chinese herbs for energyHave you tried goji berries yet?  Before you could only find them at Asian grocery stores and China town.  Now Whole Foods and health food stores everywhere are carrying them. 

Goji berries have been used in Traditional Chinese Medicine for more than 2500 years.  Sometimes they are also labeled as Lycium or Wolfberry.   Goji berries make a great snack that provide quick energy.  They have been used as a blood tonic herb in Chinese herbal medicine for this reason.  This is exactly why we included them in our Energy Booster Herb Pack.

They look a little like a dried raisin, but smaller and red in color.  Often selling for about $15.00 for half pound, they are NOT cheap!  But the health benefits of this Chinese herb are more than worth their weight. 

The value in these little berries has been demonstrated in hundreds of studies.   One of the most  recent studies done in the U.S. on goji berries found they can increase your metabolic rate and reduce body weight. So, if you're looking for a healthy snack food or a boost of energy, goji's are a great choice.

_________________

References:

http://cms.herbalgram.org/herbclip/440/121151-440.html

J Am Coll Nutr. 2011;30(5):304-309.

The Chinese Herb Licorice Root For Cavities & Gum Disease

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Chinese herbs for cavitiesOne of the most commonly used Chinese herbs is licorice root and Web MD recently mentioned how licorice root can help prevent and treat tooth decay and gum disease.

According to a new study in the Journal of Natural Products, licorice root may help keep teeth healthy.  But you won’t find the beneficial ingredients in licorice candy.  Licorice candy is mostly sugar and in the U.S. often flavored with anise oil.

The herb licorice root is in nearly every herbal formulations in Traditional Chinese Medicine.  The main reason for its popularity is its sweet flavor and its remarkable ability to guide other herbs to all 12 channels in the body.   This might sound a little odd, but if you’ve ever dug up a small licorice plant you can see the roots tend to go in all directions.  It is an interesting quality about this herb, because many herb roots don’t travel outwardly, they simple grow down. But the licorice plant has roots that are born to run.   

I was once digging up a small 5 foot tall licorice that has meandered into the wrong garden space.   As we followed the roots to clean up the space, they went 10-15 feet in several different directions. This Chinese herb seems to act the same way in the body and this is often why a very small amount, usually 3%- 6%  of Traditional Chinese herb formulas often contain licorice. (Also known as Gan Cao.)  Gan Cao helps other herbs in a formula travel to all 12 channels in the body.  This is a very rare quality, there are only a few herbs with the ability to travel to all areas of the body.

I consider it an added bonus that licorice prevents tooth decay.  A very small amount of licorice  (3%) is found in our iSleep Herb Pack.  It has traditionally been part of the 800 year old formula that iSleep is based upon.  No reason to change something that 800 years of use has already proved successful.

The Active Ingredients

The two predominant compounds in licorice, licoricidin and licorisoflavan A, were found to be the most effective in inhibiting the growth of cavity-causing bacteria. These and other compounds found in licorice root were also shown to prevent the growth of bacteria associated with periodontitis, an inflammatory disease that can destroy the bones, gums, and tissue that maintain teeth.

Warnings about the effects of licorice for those with high blood pressure need some explanation.  Studies on licorice root extract have shown a  dose of  60 grams or more per 100g formula had side effects.  However, this dose is at least 10X higher than the safe and recommended dosage used in Traditional Chinese Medicine.  Licorice has been used safely and effectively for thousand of years.  There is no documented historical use of licorice ever being used in Traditional Chinese Medicine at a dose of 60 grams in a 100g formula.  Like anything, if you abuse an herb, just like caffeine, or any drug, there can be serious side effects. It is always important to know the safe and correct dose of any medication.

P.S.   Licorice root raw slices have a lovely little flavor if you need something healthy to chew on during the day. All Chinese markets sell them because they are often thrown into soups or used for a cup of tea. A lovely Asian tradition that we now know also protects our teeth.