New Research Says Breast Cancer Triggered By Artificial Hormone Progestin

Another day and another friend/mother/sister/daughter diagnosed with breast cancer.  Today breast cancer is affecting one in every eight women sometime during their lifetime  in the USA, Europe and the UK.   Looking around at my friends, family and extended family we need no reminders of the impact of these statistics. But there is good news, actually GREAT news– medical researchers at the Institute of Molecular Biotechnology (IMBA) of the Austrian Academy of Sciences in Vienna identified a key protein that triggers breast cancer and in December 2012 received a grant of $7.4 million from the USA Congressionally Directed Medical Research Program for ongoing research.

Working for the last ten years, the research team has been able to show the synthetic female sex hormone progestin used in HRT and contraceptive pills can trigger RANKL (a protein found in breast cells).  As a consequence of this trigger, mammary cells start to divide and multiply and fail to die when they should. Moreover, stem cells in the breast become able to renew themselves, ultimately resulting in breast cancer.

The research around the artificial sex hormone progestin, used in hormone replacement therapy, HRT, and in birth control pills has been the center of  work for  Professor Josef Penninger, (IMBA director) who found the first genetic evidence that this protein RANKL is the master regulator of healthy bones and breast cell multiplication.

“Ten years ago we formulated the hypothesis that RANKL might be involved in breast cancer and it took us a long time to develop systems to prove this idea”, says Prof. Josef Penninger. ” I have to admit it completely surprised me just how massive the effects of the system were. Millions of women take progesterone derivatives in contraceptives and for hormonal replacement therapy. Since our results show that the RANKL system is an important molecular link between a synthetic sex hormone and breast tumors, one day women may be able to reduce their risk by taking blocking medicines in advance to prevent breast cancer”.

Alternative answers are available for women suffering with menopausal symptoms and want relief from hot flashes and night sweats without adding artificial hormones to their body.  Natural solutions used in Traditional Chinese Medicine are available that are safe and are made from natural plant sources, not artificial hormones.

Alternative birth control methods beyond the pill include the  IUD’s  without hormones, condoms, diaphragm,  natural rhythm method and permanent birth control in the form of tubal litigation.

The research results presented here was an  international collaboration between lead researchers at IMBA and scientists at the Medical University of Vienna; the Garvan Institute of Medical Research, Sydney, Australia; the Ontario Cancer Institute, University of Toronto, Toronto, Canada; Harvard School of Public Health, Harvard Medical School and the Ragon Institute of MGH/MIT and Harvard, Boston, USA; the Institute for Genetics, Centre for Molecular Medicine (CMMC), and Cologne Excellence Cluster (CECAD), University of Cologne, Germany; University College London, UK; and the University of Erlangen-Nuremberg, Germany.

http://phys.org/news/2011-01-progesterone-breast-cancer.html

 

 

 

 

How To Harmonize Your Health With Licorice Root

Pacific Herbs uses highest quality licorice in its formulasWe have all heard of licorice, but what it is used FOR, is a bit of a mystery. Licorice is used in nearly every Chinese herbal formula (and there are thousands) because it is known to “harmonize the formula”.

Well, what the heck does that mean?  Because licorice root can ameliorate the blood (make it better by kick starting your blood and energy), it facilitates the gastrointestinal tract’s absorption process of the herbs in the formula.  Researchers have been studying this process for years, and although scientists do not completely understand the “how” of why licorice does what it does, it is known that it does work.

Licorice root “harmonizes” herbal formulas by helping your GI tract.  Licorice (Glycyrrhiza glabra) root has been used to treat stomach ulcers, it has antioxidant qualities (the root contains flavonoids), contains amino acids that help build healthy cells and muscles, and treats upper respiratory infections, viral infections and a sore throat. Amazingly, it is classified as an adaptogen, and helps the body deal with stress! What a versatile chinese herb!

It is important to know that it’s better to use the whole herb rather than chemicals isolated from the herb because all the components of the herb together produce the desired effect. Once again, we get back to “harmony”.

All Pacific Herbs products are produced using the gold standard of pharmaceutical grade processing to ensure the most potent formulation, then stored in convenient packets that are air, water and light tight. This unique packaging keeps the all-natural compounds in our Herb Packet vital for an unprecedented 4-year shelf life while offering the convenience of a highly portable, pocket-sized pack that can be taken anywhere. The herbal ingredients are tasty and available in a powder that can be dissolved in your mouth or in hot or cold water.

Additionally, Pacific Herbs products are the most potent on the market, using the highest quality Chinese herbs available that are both safe and effective. Our manufacturing facility has state-of-the-art equipment to cook, dry and package botanicals. All Pacific Herbs Chinese herbal products are extensively tested for pesticides and other contaminants. Pacific Herbs Packets are stamped with a lot number traceable to a Certificate of Analysis (COA) of testing date. Manufacturing is under strict Current Good Manufacturing Process (cGMP) and International Standards Organization (ISO) standards.

 

References: [1] Effect of licorice on the reduction of body fat mass in healthy subjects. Armanini D, De Palo CB, Mattarello MJ, Spinella P, Zaccaria M, Ermolao A, Palermo M, Fiore C, Sartorato P, Francini-Pesenti F, Karbowiak I. J Endocrinol Invest. 2003 Jul;26(7):646-50. [2] Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application. Armanini D, Nacamulli D, Francini-Pesenti F, Battagin G, Ragazzi E, Fiore C. Steroids. 2005 Jul;70(8):538-42. Epub 2005 Apr 12. [3] The treatment of atopic dermatitis with licorice gel. Saeedi M, Morteza-Semnani K, Ghoreishi MR. J Dermatolog Treat. 2003 Sep;14(3):153-7. [4] The efficacy of licorice root extract in decreasing transaminase activities in non-alcoholic fatty liver disease: a randomized controlled clinical trial. Hajiaghamohammadi AA, Ziaee A, Samimi R. Phytother Res. 2012 Sep;26(9):1381-4. doi: 10.1002/ptr.3728. Epub 2012 Feb 6. Other Sources: Encyclopedia of Dietary Supplements, second edition, ed, Paul M. Coates, 2005, Marcel Dekker, New York, pp. 479 – 486.

How To Relieve Menopause Symptoms Whithout HRT (HRT Linked To Breast Cancer)

Breast cancer alternative therapies beyond HRTHow many women do you know that have been diagnosed, are being treated for, have survived, or even lost the battle against breast cancer? The current statistic is that 1 in 8 women will get breast cancer!

Breast cancer is occurring in alarming numbers of American women and nobody, not even the top doctors on the subject i.e. Dr. Susan Love, (who I recently heard at a conference),  have definitive answers regarding the causes. 

During menopause, many women turn to HRT for relief. Evidence linking breast cancer with HRT (Hormone Replacement Therapy) was recently released. This study, the largest ever done, was called the Women’s Health Initiative (WHI).  It was first released in 2002 and now, more evidence from researchers following these women have found that HRT significantly increases a woman’s risk of being diagnosed with invasive type of breast cancer and cause death. 

The new evidence suggests:

  • high dose HRT increased a woman’s risk more than low-dose HRT, and
  • combination HRT, both estrogen and progesterone carries an increase risk over estrogen only HRT.

After the initial WHI report was released in 2002, HRT use declined and a drop in breast cancer diagnoses was also evident.

“What’s important about this study is that it really provides tremendous clarity regarding the risks of hormone replacement therapy,” says Dr. Freya Schnabel, of New York University’s Langone Medical Center.

“I think from this point onward any woman who’s considering taking hormone replacement therapy will need to genuinely consider these risks,” says Schnabel.

What I believe is most important  for women suffering from menopause symptoms such as  hot flashes, night sweats, irritability etc,  is to realize there are other options beyond HRTNatural herbal remedies for menopause have been proven effective and have been used for generations of women.  Women who chose to see health providers such as Acupuncturists, Homeopaths, Naturepaths and other Complementary Medicine practitioners know there are many other options for natural menopause relief. 

Women really don’t need to suffer with hot flashes, poor sleep and low libido. Natural Menopause Relief does exist and it does work.   If you are suffering with menopause symptoms, learn about other safer options than HRT.

 

 

Natural Weight Loss Herbs- Skinny Boost

This is an informative video about Skinny Boost, the new herbal formula from Pacific Herbs!  It is the number one weight loss herbal formula used in Japan today, and has its roots in Traditional Chinese Medicine. This herbal remedy was first written down in 1070 AD and has been used ever since then. Skinny Boost Herb Pack is a time-tested weight loss remedy that helps improve metabolism, helps with elimination and gives your digestive system a boost so you can process and use what you eat more effectively. Give Skinny Boost a try today. We know you're going to love it. More about Skinny Boost here.

 

Midol For Period Cramps – Now On FDA Watch List For Serious Side Effects

The US Food and Drug Administration (FDA) has added all acetaminophen containing products to its quarterly list of products to monitor because of serious risks or new safety information. The side effects include liver disease or liver complications and skin rashes according to the FDA website. (www.FDA.gov)

 

The quote below is direct from the FDA website:

"What you may not realize is that more than 600 medications, both prescription and over-the-counter (OTC), contain the active ingredient acetaminophen to help relieve pain and reduce fever. Taken carefully and correctly, these medicines can be safe and effective. But taking too much acetaminophen can lead to severe liver damage."

 

If you are taking a OTC pain reliever like Midol, Tylenol, Premsyn PMS (a brand name of acetaminophen) for menstrual cramps for several days every month then consider other options for your pain. Period pain is often times one of the main reasons young women take OTC pain relievers and they often not understanding the risks.  Doubling up on acetaminophen by taking a cold and flu product or drinking alcohol while taking this OTC pain killer can cause serious liver damage.

 

If you have unrelenting menstrual cramps and period pain each and every month. Run, don't walk to this link and the book, "Stop Your Bitching…naturally!  A Step By Step Guide to Balance Your Hormones and End PMS & Menstrual Cramps".  You'll have all the answers you need to get off the liver damaging pain killers like acetaminophen.

 

 

Is China Ripping Off American Ginseng?

GinPacific Herbs Highest quality Siberian ginseng seng is one of the most popular Chinese herbs in the world and if you live in China, it is one of the most popular ways to promote health and virility.  

 

But why does most of the American ginseng get exported to China and Korea? 

 

Asian cultures have been using ginseng for thousands of years and place a high value on the American grown variety. Amazing, but true, China has been importing American ginseng for nearly 100 years since it was first discovered in the Northern mid-western region. In fact, Wisconsin's most valuable export has nothing to do with the dairy industry, or corn or wheat.  It's all about the ginseng production every year.

 

Wisconsin  is producing 95 percent of America's ginseng. U.S. demand for ginseng is still very low and the best price can be fetched in Asia. 

 

Good to know we have at least one export that China wants from us. Wisconsin governor Walker is in China this week and a deal with Tong Ren Tong, the oldest continually operated Chinese herb store in China has just been signed to export Wisconsin grown ginseng.  Maybe one day soon Americans will learn the value of this incredibly powerful herb.

 

We carry American Ginseng in our store here!

 

Energy Drinks With Carnitine Dangerous Link For Heart Disease

A study just released from the Cleveland Clinic in Ohio shows energy drinks with carnitine, a common additive not always disclosed on the labels, has been tied to heart disease.  The amount of carnitine found in energy drinks varies and may be harmful especially in doses of more than 3 grams daily.  The Cleveland Clinic study showed carnitine contributes to hardening of the arteries.

The research group, led by Dr. Hazen, section head of preventive cardiology and rehabilitation, found the link between heart disease and carnitine and the bacteria in the intestine that digests carnitine.  If you ever wondered why docotors recommend limiting red meat in your diet if you have heart issues, it it’s because carnitine is also found in red meat.

“It’s shifting their [gut] flora to one that’s more likely to promote atherosclerosis or hardening of the arteries,” said Dr. Hazen.  “I wouldn’t want my family members drinking these.”

 

Chinese Herbs Reduce Hot Flashes Says American Menopause Society

HT Hormone Therapy Risks

The American Menopause Society recently published the results of a study on the use of Chinese herbs as a menopause treatment.  It's always nice to see a clinical trial like this published in English (many are in Mandarin only)  and this study was completed in a manner consistent with top notch clinical protocol.  The study was double-blind, randomized and controlled…..ahhhh the gold standard for clinical research.

 

Chinese Herbal Formulas Can Reduce Menopausal Hot Flashes Safely and Effectively

The women in the study were experiencing menopausal hot flashes and were between the ages of 40 to 50 years old.  The participants drank either a concentrated extract of herbal granules twice daily for 12 weeks or a placebo, fake herbal tea.  The women who drank the Chinese herb remedy found their hot flashes dropped by 62%.  Most importantly, the dosage of herbs was discussed in this trial and the participants used 15 grams of concentrated extracts in a sachet each day.  (See Menopause Relief Herb Packet herbal granules here)
 
 
It is important to note the herbs were dried into granules and no pills or capsules were used in this trial. Pills and capsules always contain fillers. It is also very difficult to take 15 grams (15,000 milligrams) of herbal concentrate when taking pills or capsules because it requires a high number of pills to be swallowed.  In this case it would be 15-20 pills per dose.
 
 
THE TREND CONTINUED

Even three months after the study ended, the participants said their hot flashes did not increase after the study ended and they stopped using the menopause herbal remedy. This study shows, compared with Hormone Replacement therapy, Chinese herbs are a safe and viable alternative for menopause symptoms. 

 

Although previous studies have found that Chinese herbs can help reduce hot flashes, those studies were not of the same quality methodology as this study, according to the researchers at Menopause: The Journal of The North American Menopause Society.

 

SOURCE: Menopause: The Journal of The North American Menopause Society, online February 25, 2013.

Bio-Identical Hormones and Menopause Symptom Relief

Soy for menopause or bio-identical homrmonesThe question many women suffering with menopausal hot flashes and night sweats are asking is whether bio-identical hormones such as progesterone cream and phytoestrogen (plant sourced estrogen) are safe and effective AS  the chemical hormones found in hormone replacement therapy (HRT) drugs?

 

Many women today are being told "bio-identical" hormones are identical to those your body makes. Even though progesterone and estrogen bio-identical creams may be closer to what your body produces there are certainly risks in using any hormone therapy.   Some doctors believe the risks are just as great as taking an hormone replacement therapy drug (HRT) others believe the jury is still out because we have no long term data since these products are still very new to the market.  Risks may be tied to the dosage which varies greatly from women to women.

 

Bio-identical hormones made from plant sources may be perfectly safe in low doses, which is the way we would ingest these chemicals found in yams, soy beans and a handful of herbs but at higher doses may be harmful. Nearly every substance found in nature can be safe in minute doses yet toxic at a higher dose. Even water can kill us when taken in to large a dose over a very short time period.  Knowing what dose is right for your body can be tricky depending on blood, urine and saliva testing which may not give an accurate reading of circulating hormones in your blood which changes daily and even hourly.

 

Bio-identical hormones, make no mistake can be just as powerful and dangerous as taking a prescription hormone replacement drug.  Phytoestrogen  used in minute doses the way we find in nature may be completely safe and effective.  Asian women have a long history of eating soy beans nearly everyday of their life from childhood through adulthood and experience very few menopausal symptoms.  The isoflavones in soy are known to act as a hormone balancing chemicals.

 

So, which should you choose, bio-identical hormones or synthetic hormone replacement therapy for your menopausal symptoms?  How about neither!   There is a third option that women in Asia have used for centuries and the Western world is just beginning to see on store shelves.  Traditional Chinese herbs are another option for menopause symptom relief.   You can learn more about it here.

 

Herbal Medicine Honors For Dr. Guo

My favorite nonprofit organization has just announced the recipient for a very special award and I wanted to share the news because it has everything to do with Chinese herbs, one of my favorite topics to write about.

 

ABC also know as American Botanical Council in Austin Texas just announced its “Excellence in Botanical Research Award” recipient for 2013 will be,  Professor De-an Guo, PhD, of Shanghai, China.
Dr. Guo’s research has centered on Traditional Chinese Medicine (TCM) quality control, biochemistry, and metabolism; his phytochemical investigations of traditional Chinese herbal medicines have resulted in the identification of 100 new chemical entities. In addition to his professorship, Dr. Guo serves as director of the State Engineering Laboratory for TCM Standardization Technology and as director of the Shanghai Research Center for TCM Modernization at the Shanghai Institute of Materia Medica of the Chinese Academy of Sciences. He earned his doctorate in pharmacognosy from Beijing Medical University’s School of Pharmaceutical Sciences in 1990, and conducted his postdoctoral studies in the department of chemistry and biochemistry at Texas Tech University in Lubbock, Texas.
Among his many accomplishments, including more than 430 published scientific papers to date, Dr. Guo acted as the vice-editor-in-chief of the 2005 edition of the Pharmacopoeia of the People’s Republic of China and editor-in-chief of the 2010 edition. At present, he sits on the editorial boards of several highly respected international scientific journals, including Planta Medica and Phytomedicine. Dr. Guo is an expert committee member of the United States Pharmacopeia and a member of the ABC Advisory Board.
“Professor Guo is not only an established scientist, he has provided leadership in the modernization of TCM,” said past recipient of ABC’s Farnsworth Award, Professor Ikhlas Khan, PhD, a research professor of pharmacognosy and associate director of the National Center for Natural Products Research at the University of Mississippi. “He is a deserving recipient and I am proud to call him my friend.”

 

All I can say is WOW!   Dr. Guo is more than deserving and a life time of research in the field of Chinese herbs and Traditional Chinese Medicine is nothing short of inspiring.  Congradulations Dr. Guo.
ABC Founder and Executive Director Mark Blumenthal said; “He is clearly one of the leading figures in scientific medicinal plant research in China, a country with a vast spectrum of traditionally used medicinal plants that are undergoing modern scientific research and validation.”

Chinese Medicine From A Western Medicine Viewpoint

How a Harvard-trained doctor began to appreciate Traditional Chinese Medicine, TCM.

by Leana Wen, M.D.

As a child growing up in China, I was always aware of Traditional Chinese Medicine (TCM). TCM is what we refer to as Eastern medicine, in contrast to the Western medicine we know from U.S. hospitals. I never understood much about TCM, only that it somehow involves herbs and that many Chinese people used it. The more I progressed in my medical training in major U.S. academic centers, the more distanced I felt from TCM. Why should I learn about something that lacks evidence, when there’s so much to know about for which there is good research?

 

Last fall, I went to China on a research trip. While my study is primarily on its Western medical system, I was so fascinated by what I learned of Eastern medicine that I spent many free evenings observing TCM practitioners. There is so much I didn’t know. As a discipline, TCM is far too complex for me to understand in my short observation, but there are some very important “lessons from the East” that are applicable to our Western medical practice:

 

#1. Listen—really listen. The first TCM practitioner I shadowed explained to me that to practice TCM is to “listen with your whole body”. Pay attention and use every sense you have, he said. I watched this doctor as he diagnosed a woman with new-onset cervical cancer and severe anemia the moment she walked into his exam room, and within two minutes, without blood tests or CTs, sent her to be admitted to a (Western) medical service. I’ve seen expert clinicians make remarkable diagnoses, but this was something else!

 

“How could you know what you had and that she needed to be admitted?” I asked.

“I smelled the cervical cancer,” he said. “I looked and saw the anemia. I heard her speak and I knew she could not care for herself at home.” (I followed her records in the hospital; he was right on all accounts.)

#2. Focus on the  diagnosis. I watched another TCM doctor patiently explain to a young woman with long-standing abdominal pain why painkillers were not the answer.

“Why should we treat you for something if we don’t know what it is?” he said. “Let’s find out the diagnosis first.” What an important lesson for us—to always begin the diagnosis.

 

#3. Treat the whole person. “A big difference between our two practices,” said one TCM doctor, “Is that Western medicine treats people as organs. Eastern medicine treats people as a whole.” Indeed, I watched her inquire about family, diet, and life stressors. She counseled on issues of family planning, food safety, and managing debt. She even helped patients who needed advice on caring for the their elderly parents and choosing schools for their child. This is truly “whole person” care!

 

#4. Health is not just about disease, but also about wellness. There is a term in Chinese that does not have its exact equivalent in English. The closest translation is probably “tune-up to remain in balance”, but it doesn’t do the term justice, because it refers to maintaining and promoting wellness. Many choose to see a TCM doctor not because they are ill, but because they want to be well. They believe TCM helps them keep in balance. It’s an important lesson for doctors and patients alike to address wellness and prevention.

#5. Medicine is a life-long practice. Western medicine revers the newest as the best; in contrast, patients revere old TCM doctors for their knowledge and experience. Practicing doctors do not rest on their laurels.

“This is a practice that has taken thousands of years to develop,” I was told. “That’s why you must keep learning throughout your life, and even then you will only learn just a small fraction.” Western medicine should be no different: not only are there new medical advances all the time, doctors need to continually improve their skills in the art of medicine.

 

#6. Evidence is in the eyes of the beholder. Evidence-based medicine was my mantra in Western medical training, so I was highly skeptical of the anecdotes I heard. But then I met so many patients who said that they were able to get relief from Eastern remedies while Western treatments failed them. Could there be a placebo effect? Sure. Is research important? Of course. But research is done on populations, and our treatment is of individuals. It has taken me a while to accept that I may not always be able to explain why—but that the care should be for the individual patient, not a population of patients.

“In a way, there is more evidence for our type of medicine than for yours,” a TCM teacher told me. “We have four thousand years of experience—that must count for something!”

 

There is so much I have not covered about TCM. Its practices vary regionally, and no doubt, there are more and less capable practitioners (as there are in Western medicine). More research into TCM methods will be important. However, regardless of whether we Western doctors want to prescribe TCM treatments, we should recognize there is much to learn from Eastern medicine, including what it means to be a physician to really care for our patients. Upon my return from China, I, for one, have a new found appreciation for Eastern medical practice a renewed understanding of holistic medical care.

Yale Says Chinese Herbs Help Chemotherapy Effectiveness

Chinese herbs in the Wall Street Journal?  Undoubtably not the place you would expect such a story.  

 

Since the research was done at Yale University, why not?  Turns out a combination of four herbs used for about 1800 years in Chinese Medicine has been studied through Yale University and is reported to “enhance the effectiveness of chemotherapy in patients with colon cancer”.

 

The formula/combination of herbs is called Huang Qin Tang (Scutellaria Decoction). In early trials this four herbs  have been found effective at reducing the side-effects of chemotherapy, including diarrhea, nausea and vomiting.   (I think everyone knows a cancer patient that would love to get rid of those side-effects.)   The herbs are also being reported to “bolster colon-cancer treatment”.1

 

Will this study, help hurdle Traditional Chinese herbal medicine into mainstream American cancer therapy?  Time will tell.  Chinese herbs have been used for centuries safely and effectively and are the first medicine given before drugs throughout Asia.

 

 

 

The scientific team led by Yung-Chi Cheng, an oncology researcher at Yale University was funded in part by the National Cancer Institute, is planning to begin Phase II clinical trials. Many conventional medications are derived from individual chemical agents originally found in plants. In the case of Huang Qin Tang, however, scientists so far have identified 62 active chemicals in the four-herb combination that apparently need to “work together” to be effective.

 

Josephine Briggs, head of the National Center for Complementary

and Alternative Medicin (CAM) said about this herbal combination,

“It’s polypharmacy,” or the equivalent of several drugs being administered at once.

Dr. Cheng began his research on Huang Qin Tang about a dozen years ago when he sought a better way of dealing with the chemotherapy’s side effects.  Dr. Cheng, who grew up in Taiwan, and turned to Traditional Chinese Medicine, (TCM) which often uses herbal combinations for gastrointestinal problems. He decided to test whether it could help cancer patients without compromising the effectiveness of the chemotherapy.

 

The Chinese herb formula Huang Qin Tang contains:  Huang Qin 36%, Da Zao 16%, Bai Shao 24%, and Zhi Gan Cao 24%. Scientists have found over 62 chemicals when these four herbs are cooked in an aquaous solution, boiled in water.

The potential in Chinese herbal medicine is vast indeed.  

What will they find next?

 


Note:

Chinese herbs in places like Japan, Taiwan and China have been used for centuries and their reputation in the healthcare system is undeniably successful. Chinese herbal medicines health insurance coverage is part of the national health insurance in these Asian countries